After a median follow-up of 15 months, 135 of the 514 patients treated with pembrolizumab and 216 of the 505 patients treated with placebo

"Our study suggests that assessing the abundance of macrophages and the contextual presence of CD8 T-cells—for example by measuring gen

Researchers concluded that these findings are an example of the “obesity paradox” in melanoma—the occurrence observed in some types of cance

The protein KMT2D, a mutated gene involved in skin cancer, is also a key driver in guiding the renewal of epithelial tissues.

“We think the combined use of demethylase blockers and targeted immunotherapy might be extremely effective [for treating melanoma],” said st

“This approach is particularly powerful because it allows us to expose the immune system to many different cancer-specific epitopes simultan

The G protein-coupled estrogen receptor (GPER), once activated and combined with anti programmed death(PD)-1 inhibitor therapies, extended s

“Our findings challenge the previous school of thought that immunotherapy would offer little benefit to patients with desmoplastic melanoma