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Pathway for Langerhans cell skin/immune system communication identified
Immune cells, pictured here in bright teal, occupy the epithelial layers between the skin surface and its stem cells and act as a system regulator. (Photo by: Fuchs lab) Researchers have discovered a regulatory circuit connecting the skin surface to stem cells via Langerhans immune cells (LCs) that act as immune system regulators. They published their results in Science. This circuit acts like a “rheostat” that continuously fine-tunes the stem cells’ response to the environme
John Evans
5 minutes ago3 min read


VIDEO: Medical students influenced by social media regarding acne treatments
Social media use was associated with unsupervised use of acne treatments, specifically among medical students
Jeremy Visser
3 days ago1 min read


Call for entries: 5th annual short essay competition for Canadian dermatology residents
Derm.city is pleased to announce the 5th annual short essay competition on the topic of Inclusivity, Diversity and Equity in Dermatology. This essay competition is organized by the Dermatology Industry Taskforce on Inclusion, Diversity and Equity (DiTiDE), an unincorporated, “ad hoc” committee consisting of Canadian life sciences managers and executives, physicians, and allied parties who are committed to improving the patient experience and outcomes of underrepresented skin
Allan Ryan
4 days ago2 min read


mRNA vaccine/pembrolizumab combo reduces post-surgery melanoma recurrence, death risk
In a new study, adding an individualized mRNA-based vaccine to post-surgery pembrolizumab immunotherapy for high-risk melanoma reduced the risk of melanoma recurrence or death by 42% compared with pembrolizumab alone. The findings were announced in a presentation at the ESMO (European Society for Medical Oncology) Congress 2026 in Madrid. According to a press release from the Melanoma Institute Australia, positive results in melanoma suggest this personalized approach may ena
John Evans
Oct 302 min read


VIDEO: Vitamin B5 derivative may be potential treatment for PsO
Patients taking tablets containing a vitamin B5 derivative known as pantethine experienced improved psoriasis symptoms
Jeremy Visser
Oct 271 min read


Skin bacteria a new source of antimicrobials?
Lindsay Kalan (right) and MSc student Jordana Ferro examine a dish containing skin-associated bacteria. Photo courtesy McMaster University News The human skin microbiome may be an untapped source of new antibiotics and other antimicrobial agents, researchers at McMaster University report. In a study published in the journal Nature Communications, the investigators swabbed more than 30 volunteers at eight body sites representing distinct microenvironments—including the neck, n
Allan Ryan
Oct 262 min read


ABL1, ABL2 drive MAPK resistance and immune suppression in melanoma
New research shows that melanoma cells not only develop resistance to MAPK (Mitogen-Activated Protein Kinase) inhibitors commonly used to treat it, but also actively suppress the immune cells that would otherwise help eliminate melanoma. The study, published in Nature Communications, identified two cell proteins, ABL1 and ABL2, as key drivers of both processes. These proteins help control cell functions such as growth, survival, and communication with other cells, and when th
John Evans
Oct 232 min read


VIDEO: Children of melanoma survivors have twice the lifetime risk of melanoma
Children of parents who have been diagnosed with melanoma are twice as likely to develop melanoma themselves, due to biological factors, environmental factors, and behaviours.
Jeremy Visser
Oct 201 min read
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