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Dupilumab restores skin barrier in young children with AD
Child with Atopic Dermatitis Photo by Eisfelder via Wikimedia Commons A new study shows that treatment with dupilumab significantly restores skin barrier function and reduces inflammation in children aged 6 to 11 years with moderate-to-severe atopic dermatitis (AD). Researchers found improvements not only in visible AD lesions but also in clinically unaffected skin, highlighting the systemic nature of the disease. The findings were published in Annals of Allergy, Asthma & Imm
John Evans
32 minutes ago2 min read


VIDEO: Alopecia areata linked to higher risk of AD in patients
Patients with moderate to severe alopecia areata have a higher risk of developing AD.
Jeremy Visser
3 days ago1 min read


Pro-inflammatory M1 macrophages induce an inflammatory, invasive phenotype in melanoma cells
Melanoma cells with the cell membrane protein CD44 stained in red and the nucleus in blue. Dil-labelled extracellular vesicles taken up by cancer cells are shown in green. Image by Kaisa Mäki-Mantila. Pro-inflammatory macrophages may do more than mark an inflamed tumour microenvironment; they may help drive melanoma toward a more invasive phenotype, according to new data from the University of Eastern Finland. The findings, published in Cell Communication and Signaling , posi
Allan Ryan
4 days ago2 min read


Australian children developing fewer moles
Photo by Amanda Mills, USCDCP, via Pixnio A long-running Queensland, Australia, study has found children are developing significantly fewer moles than their peers were 25 years ago, with predictions of a major reduction in future melanoma risk. The Brisbane Twin Nevus Study, published in the British Journal of Dermatology , tracked the development of moles in twins and their siblings who turned 12 each year from 1992 to 2016. There were a total of 3,957 participants living i
John Evans
7 days ago2 min read


VIDEO: Researchers develop nanoparticles to remove melanoma with low-power laser light
Researchers at Oregon State University have developed a new nanoparticle to allow the removal of melanoma tumours using low-power laser light.
Jeremy Visser
Mar 41 min read


How testosterone increases severity of bacterial skin infections
This laboratory image shows Staphylococcus aureus bacteria streaked in the shape of a sex steroid, like testosterone. The left shape is of wild-type S. aureus, with the lighter halo around the shape indicating hemolysis, or the breakdown of red blood cells, releasing their hemoglobin into the surrounding fluid. The right shape is a quorum-sensing mutant strain of S. aureus, which cannot damage blood cells. Photo courtesy UT Southwestern Testosterone, long implicated in sex-ba
Allan Ryan
Mar 22 min read


Infection-related changes in neutrophil behaviour can trigger psoriasis flares
Photo by Bobjgalindo via Wikimedia Commons A common strep throat infection can trigger guttate psoriasis by altering the behaviour of key immune cells, according to a new study from Karolinska Institutet in Solna, Sweden. The findings, published in eBioMedicine , suggest how an infection can lead to sudden skin inflammation, particularly in children and young adults. In the study, the researchers analyzed blood and skin samples from patients with guttate psoriasis using singl
John Evans
Feb 272 min read


VIDEO: Researchers develop dissolved bubble microneedle patch for acne vulgaris
Researchers have developed a dissolved bubble microneedle patch that simultaneously delivers hydrophilic and hydrophobic medications into the skin of acne vulgaris patients.
Jeremy Visser
Feb 251 min read
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