In photodynamic therapy, a light-sensitive drug accumulates in cancer cells and is then activated by light, producing cell-killing molecules. Microneedles can help deliver the drug and distribute light more effectively within non-melanoma skin cancer. Image by M. Requena et al. A biodegradable microneedle patch designed to deliver treatment through the skin may also guide and scatter light, potentially allowing photodynamic therapy (PDT) to treat nonmelanoma skin cancers more

Schematic overview of the pathological skin-bone marrow axis driving psoriasis, based on findings from Kumamoto University researchers. The study revealed that inflamed skin produces G-CSF, which travels to the bone marrow to stimulate emergency granulopoiesis and the overproduction of neutrophils. These neutrophils then infiltrate the skin to worsen inflammation. As demonstrated in the research, experimental therapeutic interventions blocking either G-CSF (anti-G-CSF) or neu

GLP-1 receptor agonists may have potential applications as adjunct therapy for PsO, AD, HS, chronic wounds, and other skin conditions.

Ampyrone increases pigmentation in a human 3D epidermal model, The top row shows visible epidermal darkening after treatment every other day with ampyrone for 21 days as compared to negative control. The bottom row shows magnification of epidermal cells revealing increased melanin synthesis in the ampyrone treated melanocytes as compared to negative control. Positive control is alpha-melanocyte stimulating hormone (αMSH) plus beta-fibroblast growth factor (βFGF). Photo by Dr.

Ali Haider, a graduate student at HU and WPI-SKCM2 and first author of the study, observes the skin structure using confocal microscopy to investigate collagen organization and extracellular matrix remodelling. Photo by Ali Haider / Hiroshima University An international team led by researchers at Hiroshima University has developed a new way to detect subtle, early-stage changes in human skin collagen before any visible signs of damage appear. In the study, published in ACS Na

Rates of viral skin diseases have been rising globally, with the highest icreases among children and the elderly