Tyrosinase (Tyr) catalyzes hydroquinone (HQ) oxidation via two main pathways. The HBQ pathway directly oxidizes HQ to 2-hydroxy-1,4-benzoquinone (HBQ), which dimerizes and forms hydroquinone-eumelanin (HQ-EM). The BQ pathway involves dopaquinone (DQ)-mediated redox exchange producing p-benzoquinone (BQ), which reacts with cysteine (Cys) to form 2-S-cysteinylhydroquinone (Cys-HQ) and further oxidizes to hydroquinone-pheomelanin (HQ-PM). These pathways illustrate the enzymatic

46.3% of female patients with psoriasis have been exposed to at least one type of intimate partner violence.

Photo by curretett on Freeimages.com Young adults who use tanning beds may be aging their skin cells at a molecular level much faster than their chronological age suggests, according to a new study from the University of California, San Francisco (UCSF) and Northwestern University. The research, published December 12 in Science Advances , reports that tanning bed users in their 30s and 40s harbour more mutations in their skin cells than nonusers who were in their 70s or 80s.

Photo courtesy Morguefile.com Researchers have discovered a previously unknown molecular mechanism that contributes to psoriasis development, a discovery that represents a potential biomarker and treatment target. The study, published in Cell Death & Differentiation , shows that the fatty acid-binding protein FABP5 drives ferroptosis, a particular form of cell death, and amplifies inflammatory processes in the skin. Blocking this protein significantly improved the skin change

Probiotics as adjunctive therapy for acen vulgaris do not result in a statistically significant improvement in disease severity.

Illustration courtesy Juliet M. Pullar et al. J Invest Dermatol 2025 Oct. 29:S0022-202X(25)03509-2 A new study from the University of Otago in Christchurch, New Zealand, has found that dietary vitamin C intake directly enhances collagen production and skin renewal, offering clinical confirmation that nutrition may play a central role in skin physiology. Published in the Journal of Investigative Dermatology , the investigation established a strong, dose-responsive relationship